pharma world: 10/04/08

Goodman & Gilman's The Pharmacological Basis of Therapeutics, 11th Edition?

Laurence Brunton / John Lazo / Keith Parker,
McGraw-Hill | ISBN 0071422803 | 11th Edition : November 2005 | CHM | 1984 Pages | 88,0 Mb Approx

The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the desert island book of all medical you can own just one pharmacology book, this is it.
LINK:-http://rapidshare.com/files/148477219/tgg_pharmacol_therapeu.zipashu
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Modern Pharmacology With Clinical Applications 6th.Ed
The Sixth Edition of this updated and comprehensive textbook is designed to be used during a single semester, the book focuses on the clinical application of drugs within a context of the major principles of pharmacology. It is designed to serve students in medicine, osteopathy, dentistry, pharmacy and advanced nursing, as well as undergraduate students.

Book Info:
Published in 2003
Author Charles R Craig
ISBN 0781737621 Size 16.70MB
LINK:-http://rapidshare.com/files/31008244/Modern_Pharmacology_With_Clinical_Applications_6th.Ed.rar

Introductory Clinical Pharmacology

Bonnie J. Smith and Sally S. Roach, «Introductory Clinical Pharmacology», 7th Study Edition
Lippincott Williams & Wilkins | ISBN 0781736978 | July 2003 | PDF | 256 Pages | 11 Mb

This superb study guide reviews in detail each critical area of nursing pharmacology, and helps you define your role in the safe and effective administration of today's most commonly used agents.

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http://rapidshare.de/files/21135528/Introductory_Clinical_Pharmacology.part1.rar
http://rapidshare.de/files/21135842/Introductory_Clinical_Pharmacology.part2.rar

Textbook of Receptor Pharmacology

The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the University College of London for the past three decades. Its innovative format united four major approaches to the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems. The second edition builds on this foundation. This edition streamlines the material and focuses on cell membrane receptors along with their immediate signal transducers. The section on the molecular structure of receptors reflects the advances in this area. This edition also includes two restructured new chapters, one on G-proteins and one on tyrosine kinases, as signal transductors. Several chapters also contain problems for students to solve as well as worked-out solutions.

link:-http://rapidshare.com/files/45791393/Textbook_of_Receptor_Pharmacology.pdf

The current science of pharmacology-and its clinical applications-at your fingertips

Now in its 25th year of publication, Basic and Clinical Pharmacology is the most up-to-date and complete pharmacology textbook available. Through nine previous editions it has set the standard for concise and easy-to-read, yet comprehensive coverage of pharmacology. The text's integration of basic with clinical science makes it well suited for an integrated organ-system-based curricula as well as the more traditional curricula.

Features
# In-depth coverage of key pharmacology topics, from basic principles to pharmacologic considerations for autonomic, cardiovascular-renal, smooth muscle, CNS, endocrine, antimicrobial, and chemotherapeutic and immunotherapeutic drugs
# Updated with dozens of new, recently approved drugs, including monoclonal antibodies
# Detailed review of the mechanism of action and toxicities of traditional and newer drugs
# Critical discussions of treatment strategies and recommended drugs for all major diseases
# Valuable section on toxicology that provides an introduction to occupational and environmental toxicology; heavy metal intoxication and chelators; and management of the poisoned patient
# Ready-to-use, study-enhancing features, including special interest boxes, lists of common preparations, and dosage information
# Unique evidence-based chapters on abused drugs; special aspects of perinatal, pediatric, and geriatric pharmacology; and over-the-counter drugs, herbal medications, and nutritional supplements
link:-http://rapidshare.com/files/106487856/BASIC___CLINICAL_PHARMACOLOGY_-_10th_Ed.__2007_.rar

Instant Clinical Pharmacology

Evan J. Begg, "Instant Clinical Pharmacology (Instant)"
Wiley-Blackwell | 2002-12-20 | ISBN: 1405102756 | 120 p | PDF | 1 MB

Instant Clinical Pharmacology is a short introductory text, which explains the principles behind the prescribing process. The book provides essential information about the core topics in clinical pharmacology and bridges the gap between basic pharmacology and the therapeutic use of drugs. Written for the busy medical student and junior doctor, the book provides the reader with a quick resource for understanding the principles of drug action and interaction and the use of drugs in clinical practice.

The book has been designed for ease of use and is organised into short modules. As with other titles in the Instant Series, the accessible style of one topic per page is used, accompanied by clear illustrations.

Instant Clinical Pharmacology is ideal for medical students requiring a quick overview of the topic or for review when preparing for examinations.

http://rapidshare.com/files/149083421/Instant_Clinical_Pharmacology.pdf

Apoptosis Methods in Pharmacology and Toxicology: Approaches to Measurement and Quantification

Myrtle A. Davis, "Apoptosis Methods in Pharmacology and Toxicology: Approaches to Measurement and Quantification (Methods in Pharmacology and Toxicology)"
Humana Press; 1st edition (June 15, 2002) | ISBN-10: 0896038904 | 176 pages | PDF | 2,3 Mb

"The book emphasizes techniques that can be used to quantify apoptosis, such as cell morphology, flow cytometry, laser-scanning cytometry, ELISA, and DNA microarray. The flow cytometry and ELISA sections are the best, as they are applicable to a wide range of laboratories because of their ease of use do not require any extraordinary facilities. . .The book is well written and instructive, and the techniques described can be applied easily to topics in pharmacology and toxicology as well as in general apoptosis research. A strong point is that the authors emphasize the need to combine morphological assessment of the cell with other apoptotic parameters in order to fully characterize a cell as apoptotic."-Doody's Health Science Book Review Journal
link:-http://rapidshare.com/files/62136090/Apoptosis_Methods_in_Pharmacology_and_Toxicology-0896038904.pdf

Pharmacology of Neurotransmitter Release (Handbook of Experimental Pharm)

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the books second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters.
links:-http://rapidshare.com/files/79975580/Pharmacology_of_Neurotransmitter_Release.rar

Concise Dictionary of Pharmacological Agents: Properties and Synonyms

This dictionary provides a convenient personal reference source, intended to complement more encyclopaedic works. First, there is an alphabetic, fully cross-indexed listing of pharmacologically active agents and their properties, containing details of some 4000 individual chemical agents including medical drugs in current use, experimental agents and toxins used as investigation tools. Over 10,000 alternative names are indexed, including chemical names, abbreviated chemical names, official pharmacological names, proprietary names and research code numbers. A key feature is that the properties of the agents are categorised, according to mechanism and use, into 300 classes -for each of which there are descriptive articles for which key literature and review references are provided. Second, there is an alphabetical glossary explaining the meaning of some 3000 biomedical terms from pharmacology, biochemistry, molecular biology, immunology, pathology, physiology, anatomy and microbiology. Emphasis in explanation is given to terms that can cause confusion, for example those relating to drug receptors and to endogenous mediators. Audience: This work provides indispensable information for researchers in the fields of pharmacology, medicinal chemistry and pharmaceutics, and biochemistry, as well as for medical and science writers and editors and drug regulatory officers.
link:-http://rapidshare.com/files/46229457/concisedict.rar

G Protein-Coupled Receptors: Structure, Function, and Ligand Screening

G Protein-Coupled Receptors: Structure, Function, and Ligand Screening (Methods in Signal Transduction)
Author:Tatsuya Haga , Shigeki Takeda
Publisher:CRC | Pages:336 | 2005-08-04 | ISBN:0849327717 | Pdf | 4.25 MB

With contributions from international experts in the fields of pharmacology, neuroscience, and biochemistry, this text provides an in-depth exploration of GPCRs. Coverage includes the screening of ligands for GPCRs, physiological and molecular characterizations of GPCRs, and structures of GPCRs and their ligands. The book explores current research issues in the post-genome era, particularly the identification of endogenous ligands that may lead to finding new hormones or neurotransmitters. It also discusses the determination of the tertiary structure of GPCRs, useful for understanding GPCR interactions and for the theoretical modeling of drugs.
link:-
http://www.megaupload.com/?d=07J97QLW

New Drug Development: Regulatory Paradigms for Clinical Pharmacology and Biopharmaceutics

New Drug Development: Regulatory Paradigms for Clinical Pharmacology and Biopharmaceutics
Publisher: Informa Healthcare | 2004-05-24 | ISBN 0824754654 | Pages: 500 | PDF | 5 MB

Highlighting key points from the latest regulatory requirements, this book helps those new to the world of pharmaceutical development understand regulatory steps, reduce cost by avoiding unnecessary trials, and attain guidance through each step of the drug approval process. This volume acquaints readers with procedures that determine the success of drug development projects with updated regulatory guidelines from the FDA and ICH, solutions to hurdles in application protocols, and recommendations from more than forty respected and experience officials from regulatory agencies around the globe. It covers topics related to the development of chiral drugs, liposomal products, and more.

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“Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics:
Homogeneous and Heterogeneous Approaches"
Springer | 2005-12-15 | ISBN: 0387281789 | 442 pages | PDF | 3,3 MB

The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods.
This timely and useful book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology.
link:-
http://depositfiles.com/en/files/5736370

Foundations of Pharmacokinetics

This book is divided into two parts; in the first part the principles and the methods of pharmacokinetics are described in detail, while in the second the main pharmacokinetic parameters are described, giving for each of them the definition, the principal properties, and the methods of determination. An appendix contains the important mathematical instruments used in the main part of the book, namely the operational calculus and the convolution integral.

The first part begins with the definition of pharmacokinetics, then continues with the description of the experimental method as applied to the modeling of pharmacokinetic systems. The bulk of this part is the description of the first compartmental models used in the '30's, the more modern compartmental equations developed later, the integral equations and the matrix equations.

In the second part there is a careful distinction among pharmacokinetic parameters, i.e., parameters that represent a true pharmacokinetic property, model parameters, i.e., parameters that represent a property of a specific model, and incidental parameters, i.e., parameters that represent only the result of a particular experiment.
link:-
http://rapidshare.com/files/147352611/tfounda_pharmacok.zip

"The Serotonin Receptors From Molecular Pharmacology to Human Therapeutics"

"The Serotonin Receptors From Molecular Pharmacology to Human Therapeutics"
Publisher:Humana Press | Pages:640 | 2006-06-01 | ISBN:1588295680 | PDF | 7.8 MB

A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.

http://www.megaupload.com/?d=O9L00R3I

OR
http://rapidshare.com/files/68248692/The_Serotonin.rar

Pharmacology of Neurotransmitter Release (Handbook of Experimental Pharm)

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the books second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters.

http://rapidshare.com/files/79975580/Pharmacology_of_Neurotransmitter_Release.rar

Biomarker Methods in Drug Discovery and Development (Methods in Pharmacology and Toxicology)

Within the pharmaceutical industry, the improvement of drug discovery and development efficiency and the expected personalization of medicine have become vitally important issues. In Biomarker Methods in Drug Discovery and Development, expert researchers provide a tool box for those who have a general interest in biomarker research and for those currently specializing in certain technologies but desiring an understanding of other available methodologies. Its chapters include validated, mature methods as well as new, incredibly promising protocols which aim to apply multiple technologies at different molecular levels in order to surmount the monumental and complex task of transforming the pharmaceutical research and development processes. As a volume in the Methods in Pharmacology and Toxicology series, this book offers user-friendly, step-by-step laboratory protocols for readily reproducible experiments.

Comprehensive and state-of-the-art, Biomarker Methods in Drug Discovery and Development is the perfect biomarker technical guideline and reference to stimulate more exciting biomarker research and technology development.
link:-

http://rapidshare.com/files/92800658/Biomarker_Methods_in_Drug_Discovery_and_Development.rar

Case Files: Pharmacology

Gail Stein “Case Files: Pharmacology"
McGraw-Hill Medical | 2008-04-10 | ISBN: 0071488588 | 456 pages | PDF | 1,4 MB

More than 50 clinical cases help you excel in pharmacology courses and the USMLE Step 1
The Case Files series is an award-winning learning system proven to improve exam scores. This series helps you to learn in the context of real patients instead of simply memorizing. Case Files: Pharmacology: Second Edition presents 55 clinical cases with open-ended questions which weave basic science concepts into the clinical scenario. Each case includes an extended discussion (including definitions and a pathophysiology discussion), key points, and 3-5 USMLE-style comprehension questions. The authors are experienced teachers from the University of Texas-Houston Medical School in Houston, Texas.
links:-
http://depositfiles.com/en/files/6052774

Lippincott's Illustrated Reviews : Pharmacology

Book Description
Students and faculty alike have attested to the extraordinary success rate of the Lippincott's Illustrated Reviews--the unparalleled review texts that clarify the essentials students need to know for the Boards through an easy-to-use outline format and illustration program. Now, the Pharmacology review has been updated and enhanced to ensure that students fully master the most current information.Designed and edited by top educators, the book helps the student tie together the visual and cognitive elements of learning for superior recognition and recall. More than 500 pictures and diagrams, carefully crafted to complement and amplify the text, are completely integrated with the text. Board-type questions, with detailed explanations of the answers, are included with each chapter. This new Second Edition also includes a series of illustrated case studies. A unique Infolink cross-referencing system between the Pharmacology and Biochemistry volumes of this series enables students to interrelate the two disciplines. --This text refers to an out of print or unavailable edition of this title.

Book Info
Study guide providing more illustrations than previous edition, c1992. This is a 'Millenium Update' of the c1997 version. Cross-referenced to Harvey and Champe's Lippincott's Illustrated Reviews: Biochemistry, 2nd edition. For students preparing for exams

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http://rapidshare.de/files/20887090/P2.part1.rar.html
http://rapidshare.de/files/20887566/P2.part2.rar.html

Rang & Dale's Pharmacology

Humphrey P. Rang, Maureen M. Dale ), James M. Ritter), Rod Flower , "Rang & Dale's Pharmacology"
Churchill Livingstone; 6 edition (January 25, 2007) | ISBN: 0443069115 | 844 pages | CHM | 44,5 Mb

A straightforward way to master a complex subject! This bestselling textbook presents all the knowledge you need to get through your pharmacology course and beyondusing a clear and accessible approach that makes the material easy and interesting to learn. Progressing logically from a molecular understanding of receptors and drug actions to the clinical uses of the most important groups of drugs, it delivers the latest information on cannabinoids and rimonabant, Cox 2 inhibitors, pharmacogenetics, biopharmaceuticals, and drug abuseas well as "lifestyle drugs" such as performance-enhancing substances, botulinum toxin, and Viagra. And now, online access via STUDENT CONSULT makes it an even more effective learning resource!

http://depositfiles.com/files/2026932

Herbal Products: Toxicology and Clinical Pharmacology (Forensic Science and Medicine)

Timothy S. Tracy, Richard L. Kingston , "Herbal Products: Toxicology and Clinical Pharmacology (Forensic Science and Medicine)"
Humana Press; 2nd ed. edition (May 8, 2007) | ISBN: 1588293130 | 290 pages | PDF | 1,1 Mb

Herbal Products: Toxicology and Clinical Pharmacology, Second Edition builds on the informative foundation laid by its predecessor. This fully revised and expanded second edition boasts more than 200 new
references that document efficacy studies and adverse effects and four new chapters devoted to dietary products. Practitioners and researchers will find that this volume is a comprehensive resource for
objective clinical information about the potential uses, efficacy, and safety of herbal medicines. The authors recognize that the majority of available information on dietary supplements is typically provided by
distributors and designed to sell a product rather than objectively inform consumers; therefore, the emphasis throughout is on information not readily available from any other source. Similar to the first edition, this volume is based on original studies published in peer-reviewed journals, as well as meta-analyses, systematic reviews, and other high-quality assessments by recognized experts.

http://depositfiles.com/files/2054053

Principles of Antineoplastic Drug Development and Pharmacology

Informa Healthcare | 1996-06-27 | IS

BN: 0824793145 | 760 pages | PDF | 48 MB

Details how the successful application of pharmacological principles can improve drug delivery, individualized dosing, and the circumvention of drug resistance; elucideates proven strategies for widening the therapeutic margin between antitumor effects and severe toxicity; and more.

http://www.filefactory.com/file/552daf/n/Principles_of_Antineoplastic_Drug_Development_and_Pharmacology_rar

BRS Pharmacology

Gary C Rosenfeld, David S Loose-Mitchell, "BRS Pharmacology"
Lippincott Williams & Wilkins | 2006-07-01 | 0781780748 | 372 p | PDF | 70 M

This concise review of medical pharmacology is designed for medical students, dental students, and others in the health care professions. It is intended primarily to help students prepare for licensing examinations such as the USMLE Step 1 or similar examinations. Each chapter presents specific drugs and discusses their general properties, mechanism of action, pharmacologic effects, therapeutic uses, and adverse effects. Drug lists and two-color tables and figures summarize essential drug information in all chapters. Clinically oriented USMLE-style review questions and answers with explanations follow each chapter. A comprehensive examination consisting of USMLE-style questions appears at the end of the book.

http://rapidshare.com/files/123957494/Pharmacology_4th_Ed.rar

Medical Pharmacology at a Glance

M. J. Neal, «Medical Pharmacology at a Glance»
Blackwell Publishers | ISBN 0632052449 | 2002 | PDF | 102 Pages | 16,2 Mb

Undergraduate textbook uses the double-page spread format to summarize the core principles of the field. Each section contains a clear illustration depicting the major drugs and their interactions with a particular body system and a concise account of the topic

http://rapidshare.de/files/27971448/MEDICAL_PHARMACOLOGY_AT_A_GLANCE.rar.html

Forensic Pharmacology (Inside Forensic Science)

By Beth E. Zedeck, Morris S. Zedeck"Forensic Pharmacology (Inside Forensic Science)"
Chelsea House Publications | Pages: 128 | 2006-12 | ISBN: 0791089207 | 1 MB

http://depositfiles.com/files/5637567

Biochemical Targets of Plant Bioactive Compounds: A Pharmacological Reference Guide to Sites of Action and Biological Effects

CRC, 2003 | G. Polya | ISBN : 0415308291 | PDF | ENGLSIH | 860p | 32MB

When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents. Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.

http://depositfiles.com/en/files/1794216

Saturday, October 4, 2008

PHARMACOLOGY

Foundations of Pharmacokinetics

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Saturday, October 4, 2008

PHARMACOLOGY

Foundations of Pharmacokinetics

pharma world

ashutoshpharmaworld

Subscribe To me

Topics

About Me

pharma feeds

Blog Archive

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Followers