Saturday, February 7, 2009

drug delivery

Nanobiotechnology of Biomimetic Membranes




Donald Martin, "Nanobiotechnology of Biomimetic Membranes"
Springer | 2006-12-07 | ISBN: 0387377387 | 174 pages | PDF | 3,8 MB

Nanobiotechnology of Biomimetic Membranes describes the current state of research and development in biomimetic membranes for nanobiotechnology applications. The application areas in nanobiotechnology range from novel nanosensors, to novel methods for sorting and delivering bio-active moleculres, to novel drug-delivery systems. The success of these applications relies on a good understanding of the interaction and incorporation of macromoleculres in membranes and the funamental properties of the membrane itself.



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Degradable Aliphatic Polyesters: Series: Advances in Polymer Science, Vol. 157


Publisher: Springer | ISBN: 3540422495 | 2002 | Pages: 179 | PDF | 1.3 MB

A renewed interest in aliphatic polyesters has resulted in developing materials important in the biomedical and ecological fields. Mainly materials such as PLA and PCL homopolymers have so far been used in most applications. There are many other monomers which can be used. Different molecular structures give a wider range of physical properties as well as the possibility of regulating the degradation rate. By using different types of initiators and catalysts, ring-opening polymerization of lactones and lactides provides macromolecules with advanced molecular architectures. In the future, new degradable polymers should be able to participate in the metabolism of nature. Some examples of novel polymers with inherent environmentally favorable properties such as renewability and degradability and a series of interesting monomers found in the metabolisms and cycles of nature are given.

Table of contents
A.-C. Albertsson, I.K. Varma: Aliphatic Polyesters: Synthesis, Properties and Applications.-
K.M. Stridsberg, M. Ryner, A.-C. Albertsson: Controlled Ring-Opening Polymerization: Polymers with Designed Macromolecular Architecture.-
U. Edlund, A.-C. Albertsson: Degradable Polymer Microspheres for Controlled Drug Delivery.-
M. Hakkarainen: Aliphatic Polyesters: Abiotic and Biotic Degradation and Degradation Products.-
M. Söderqvist Lindblad, Y. Liu, A.-C. Albertsson, E. Ranucci, S. Karlsson: Polymers from Renewable Resources.-


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"Local Drug Delivery for Coronary Artery Disease: Established and Emerging Applications"
Edoardo Camenzind, Ivan De Scheerder

Inf HealthCare | 2005-06-14 | ISBN: 1841840459 | 608 pages | PDF | 9 MB


Restenosis remains the Achilles heel of Percutaneous Coronary Interventions. Numerous pharmacological agents have been tested in order to reduce acute thrombosis and the hyperproliferative cellular response, and drug eluting stents-using the stent as a platform for local drug delivery-are now considered a significant breakthrough in interventional cardiology. Pioneers in the field, the editors of Local Drug Delivery for Coronary Artery Disease have assembled an excellent team of contributors who offer their experience with threatened vessel closure and restenosis, acute thrombosis, hyperproliferative cellular response, stents and local drug delivery. They share their expertise on all aspects of the field, including a discussion of results from preclinical and clinical studies, and they examine alternative methods of molecular delivery to the vessel wall. With coverage of the most current methods and applications, as well as a host of photographs illustrating their implementation, this book will serve as an excellent reference for cardiologists, pharmacologists, cardiac surgeons, and trainees.

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" Design of Controlled Release Drug Delivery Systems"
McGraw-Hill Professional; 1 edition (November 3, 2005) | ISBN: 0071417591 | 435 pages | PDF | 3,3 Mb

Written by an International team of experts, this comprehensive text offers pharmaceutical scientists and engineers working in the field, state-of-the-art design principles for the development and bioengineering of drug delivery systems/technology. Readers will find drug delivery systems presented with a particular emphasis on the design principles and their physiological/pathological basis. For each specific design principle, the contributors briefly introduce the relevant pharmacokinetics (where necessary) and include the challenges of different biological barriers that need to be overcome.

This in-depth text features detailed coverage of:
Physiological and biochemical barriers to drug delivery
Pharmacokinetics and pharmacodynamics of drug delivery
Diffusion and dissolution strategies
Prodrugs
Bioadhesive and gastric retentive systems
Physiological and biochemical barriers to drug delivery
Targeted drug delivery
Device controlled and programmable drug delivery
And more

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" Enhancement in Drug Delivery"

CRC; 1 edition (November 27, 2006) | ISBN:0849332036 | 656 pages | PDF | 6,1 Mb

Enhancement in Drug Delivery offers an accessible compendium covering a wide spectrum of methods to enhance drug delivery and absorption by various routes of administration. Drawing from a number of disciplines, it gives students and practitioners in pharmaceutics, medicine, and health-related disciplines a much-needed guide to current practices. It also provides a starting place for those working on delivery systems for new drugs or seeking to improve current systems by drawing on means applied in other routes. Organized by routes of delivery, the book covers oral, rectal, buccal and sublingual, dermal and transdermal, ocular, vaginal and uterine, nasal and brain administrations.



General Pharmacology and Toxicology textbook collections



Various authors/editors: General Pharmacology and Toxicology Textbooks
2002-2008 | ISBN: Multiple | 4800 + 5755 pages (total) | English | PDF (OCR) | 90 + 64 Mb ZIPs | Value: C$1514.75 + C$975.27


Pharmacology is the study of drug action. More specifically it is the study of the interactions that occur between a living organism and exogenous chemicals that alter normal biochemical function. It is the study of drugs, of the body's reaction to drugs, the sources of drugs, their nature, and their properties.

Pharmacology titles include:
Goodman and Gilman's Manual of Pharmacology and Therapeutics | L. Brunton et al. | 2007 | ISBN: 0071443436 | 1230 pp | 25 Mb | C$60.95
Principles of Clinical Pharmacology, 2e | A.J. Atkinson et al. | 2007 | ISBN: 0123694175 | 566 pp | 13 Mb | C$138.50
Desk Reference of Clinical Pharmacology, 2e | M. Ebadi | 2007 | ISBN: 1420047434 | 824 pp | 38 Mb | C$215.95
Human Drug Metabolism: An Introduction | M.D. Coleman | 2005 | ISBN: 0470863528 | 277 pp | 2 Mb | C$128.51
Encyclopedia of Molecular Pharmacology | S. Offermanns, W. Rosenthal | 2008 | ISBN: 3540389164 | 1344 pp | 32 Mb | C$855.84
Color Atlas of Pharmacology, 3e | H. Luellmann et al. | 2005 | ISBN: 158890332X | 414 pp | 11 Mb | C$57.50
Paediatric Drug Handling | I. Costello et al. | 2007 | ISBN: 0853696861 | 145 pp | 1 Mb | C$57.50

Toxicology, a subfield of pharmacology, is the study of the adverse effects of chemicals on living organisms. It is the study of symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people.

Toxicology titles include:
Casarett & Doull's Toxicology, 7e | C.D. Klaassen | 2008 | ISBN: 0071470514 | 1331 pp | 31 Mb | C$134.95
Fundamental Toxicology | J.H. Duffus, H.G.J. Worth | 2006 | ISBN: 0854046143 | 517 pp | 5 Mb | C$114.50
Clinical Toxicology: Principles and Mechanisms | F.A. Barile | 2005 | ISBN: 0849315824 | 474 pp | 4 Mb | C$114.50
Principles of Biochemical Toxicology, 4e | J.A. Timbrell | 2003 | ISBN: 0849373026 | 466 pp | 12 Mb | C$126.95
Goldfrank's Manual of Toxicologic Emergencies | R.S. Hoffman et al. | 2007 | ISBN: 007144310X | 1151 pp | 6.64 Mb | C$60.95
Stockley's Drug Interactions, 8e | K. Baxter | 2008 | ISBN: 085369754X | 1473 pp | 15 Mb | C$317.50
Antidotes | R.J. Flanagan, A.L. Jones | 2002 | ISBN: 0748409653 | 343 pp | 3 Mb | C$105.92

For your convenience, these collections bring together popular and up-to-date general resources in the fields of pharmacology and toxicology from across the web.

Pharmacology: Rapidshare Download (90 Mb)
http://rapidshare.com/files/193114161/Pharmacology.zip

Toxicology: Rapidshare Download (64 Mb)

http://rapidshare.com/files/193099012/Toxicology.zip
 

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