Friday, March 6, 2009

Melmon and Morrelli's Clinical Pharmacology

Melmon and Morrelli's Clinical Pharmacology
Publisher:McGraw-Hill Medical | Pages:1433 | 2000-05-25 | ISBN: 0071054065 | CHM | 14.6 MB

* Perfect for the student, primary care practitioner, and pharmacist who needs both basic and clinical information to apply therapeutics.
* A new overview chapter--plus practical steps required for optimal therapeutic decisions.
* Coverage of newly emerging advances in therapeutics.
* A new look at cost/benefit analysis of therapy.
* Increased emphasis on drug interactions, and much more.





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Oxford Textbook of Medicine

Oxford Textbook of Medicine (Three Volume Set) by David Weatherall, Edward J. Benz, David A. Warrell, Timothy M. Cox, John D. Firth
Publisher: Oxford University Press, USA | Number Of Pages: 1228 | Publication Date: 2003-03-20 | ISBN-10: 0192629220 | PDB | 55 Mb

The Oxford Textbook of Medicine provides all that any doctor needs to know to practice top-level internal medicine. It gives compreensive coverage of the epidemiology, aetiology, and mechanism of disease, as well as clear, unambiguous coverage of the diagnosis, practical management and prevention of the entire spectrum of medical disorders.
There are major introductory sections on the scientific basis of disease; and in the system-based clinical sections genetic predisposition, pathophysiology, pathogenesis, molecular mechanisms, and cell biology are covered in depth for all significant medical syndromes. Clinical descriptions of diseases are clearly and memorably written, based on the experience and insight of the authors--many of whom are among the world's most distinguished medical scientists. Chapters are not only "evidence based" but also on clinical experience and a thorough survey of all the relevant literature. Throughout, the approach of OTM is humane and ethical and, at the same time, factual, reliable, honest(especially where knowledge is limited) and rigorously scientific.
This is not just a textbook of "First World" medicine. It provides practical guidance for doctors working in a variety of medical setting the value of a logical clinical approach rather than immediate resort to expensive imaging and laboratory tests. Moore of the contributing authors than ever before are from outside Europe, including strong representation of North American medicine.
The new editorial team has ensured that the OTM continues to reflect rapid changes in medical practice: there are new sections on intensive care, alcohol and drug abuse, clinical pharmacology and therapeutics, world health, clinical trials and evidence-based medicine, adolescent medicine, sports medicine, and emergency medicine; more than half the contributors are new for this edition; and most of the text has been heavily revised. The striking new page and cover design reflect the significant changes made in this new edition.
The Textbook is illustrated by over 2000 two-color diagrams and many color Plates. The index is the most detailed and user-friendly of any major medical textbook: in an emergency, the reader can access information quickly- whether on the ward, in office or at home.
Like its predecessors, OTM4 will be the trusted and ultimate reference in libraries, hospitals, doctors' consulting rooms, solicitors' offices, press offices, and primary care practices worldwide.


A Comprehensive Guide to Chinese Medicine

Ping-Chung Leung, Charlie Changli Xue, Yung-Chi Cheng "A Comprehensive Guide to Chinese Medicine"
World Scientific Publishing Company | 2004-02 | ISBN: 9812386041 | 372 pages | PDF | 15,2 MB

This invaluable book is aimed at those who are concerned about Chinese medicine — how it works, what its current state is and, most important, how to make full use of it. The audience therefore includes clinicians who want to serve their patients better and patients who are eager to supplement their own conventional treatment.
The authors of the book belong to three different fields, viz. clinical and basic sciences, Chinese medicine and pharmacology. They provide information from their areas of expertise and concern, attempting to make it comprehensive for users. The approach is macroscopic and philosophical; readers convinced of the philosophy are to seek specific assistance.


Principles and Practice of Pharmacology for Anaesthetists



Norman Calvey, Norton Williams “Principles and Practice of Pharmacology for Anaesthetists"
Wiley-Blackwell | 2008-03-14 | ISBN: 1405157275 | 376 pages | PDF | 3,35 MB


This fifth edition of Principles and Practice of Pharmacology for Anaesthetists continues to provide a comprehensive scientific basis and a readable account of the principles of pharmacology, as well as practical guidance in the use of drugs that is relevant to clinical anaesthesia.
With these concepts in mind:
Every chapter in this new edition has been thoroughly revised and updated
An additional chapter on Adverse Drug Reactions is included
For ease of reference, the structures of many commonly used agents are featured, with their sites of isomerism, when appropriate
Recommended International Non-proprietary Names (rINNs) are generally used for generic agents, although preference has been given to the current nomenclature for adrenaline and noradrenaline.
As in previous editions, a comprehensive glossary covering abbreviations and acronyms is included to aid the reader.
Principles and Practice of Pharmacology for Anaesthetists is an invaluable resource, both for candidates of professional examinations in anaesthesia and the practising anaesthetist wishing to refresh their pharmacological knowledge.



Encyclopedia of Molecular Pharmacology



Stefan Offermanns, Walter Rosenthal, "Encyclopedia of Molecular Pharmacology"
Springer | 2008-09-25 | ISBN: 3540389164 | 1505 pages | PDF | 25.3 MB

An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.


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Human Drug Metabolism



Michael Coleman, "Human Drug Metabolism"
Wiley | 2005-11-18 | ISBN: 0470863528 | 286 pages | PDF | 1,5 MB


Drug metabolism is a core area of pharmacology. Before any drug can be licensed it is essential to know how the body metabolises the drug, and the short and long-term effects it has on the body. It is an area of rapid advancement, which brings together the fields of pharmacy, pharmacology and medicine.

This new text provides a concise, user-friendly introduction to drug metabolism that is ideal for undergraduates. Focusing on a conceptual understanding of the drug metabolism system, the book illustrates the basic mechanisms on how xenobiotics are detected, chemically modified and then eliminated from human systems.

Enjoy this great book! Brought to you by SMIRK

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Pharmacotherapy Handbook


Barbara Wells, Joseph DiPiro, Terry Schwinghammer, Cecily DiPiro, "Pharmacotherapy Handbook, 7 Ed"
McGraw-Hill Medical | 2008-10-22 | ISBN: 0071485015 | 1072 pages | PDF | 3,3 MB

Essential Pharmacotherapy Data at Your Fingertips!
Pharmacotherapy Handbook delivers the essential information you need to quickly and confidently make drug therapy decisions for eighty-four diseases and disorders. Featuring a convenient alphabetized presentation, the book utilizes text, tables, figures, and treatment algorithms to make important drug data readily accessible and easily understandable.
Features:
Consistent chapter organization that includes:. Disease state definition,. Concise review of relevant pathophysiology,. Clinical presentation,. Diagnosis,. Desired outcome,. Treatment,. Monitoring
Six valuable appendices, including a new one on the management of pharmacotherapy in the elderly.
NEW chapters on adrenal gland disorders and influenza.
The ideal companion Pharmacology: A Pathophysiologic Approach, 7e by Joseph DiPiro et al.

Introduction to Medicinal Chemistry


Introduction to Medicinal Chemistry: How Drugs Act and Why by: Alex Gringauz
Publisher: Wiley-VCH | ISBN: 0471185450 | 1996-12-27 | Pages: 736 | DJVU | 23 MB

This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.

Basic Considerations of Drug Activity.
Mechanisms of Drug Action.
Drug Metabolism and Inactivation.
Anticancer Drugs and Their Mechanism of Action.
Analgetics and Nonsteroidal Antiinflammatory Agents.
Antimicrobial Drugs I. Antimicrobial Drugs II.
Drugs Affecting Cholinergic Mechanisms.
Drugs Affecting Adrenergic Mechanisms.
Drugs and the Cardiovascular Diseases.
Drugs and the Cardiovascular Diseases II.
Psychoactive Drugs--Chemotherapy of the Mind.
Histamine Antagonists and Local Anesthetics.
Steroids.
New Developments and New Problems.
Index.


stability of drugs and dosage forms



Sumie Yoshioka, Valentino J. Stella, "Stability of Drugs and Dosage Forms"
Springer; 1 edition (November 2000) | ISBN: 0306464047 | 272 pages | PDF | 2,1 Mb

Drug products are complex mixtures of drugs and excipients and, as such, their chemical and physical stability kinetics are complex. This book discusses the stability of these dosage forms with preformulation studies through to the studies on the final products. The book is intended for graduate students, researchers and professionals in the field of Pharmaceutics and Pharmaceutical Chemistry.
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Handbook of Preformulation: Chemical, Biological, and Botanical Drugs

Sarfaraz K. Niazi (Author), "Handbook of Preformulation: Chemical, Biological, and Botanical Drugs"

Informa Healthcare | 1 edition | September 18, 2006 | ISBN: 9780849371936 | PDF | English | 6 Mb | 446 pages

"Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance..."

Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. Entirely focused on preformulation principles, this handbook provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity.

 

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